JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018 - 54

54

Journal of Clinical Urology 11(1S)

P5-10: Figure 1: Boxplots of distribution of ICIQ-UI-SF scores between the groups

P5-11 A cadaveric pilot study of bulkamid
injections for the treatment of post
prostatectomy incontinence
O'Connor E1, Solomon E2, Ockrim J1, Greenwell T1
College Hospital at Westmoreland Street, London, United
Kingdom, 2Guy's and St Thomas' NHS Foundation Trust, London,
United Kingdom
1University

Introduction: Postprostatectomy incontinence (PPI) is a
bothersome complication of radical prostatectomy.
Although most men recover from PPI, some men continue
to have persistent urinary incontinence.
Treatment of small volume persistent PPI with male sling
or an artificial urinary sphincter may be overly invasive and
the concept of intraurethral injection is very appealing in
this situation. Bulkamid® is a non-particulate polyacrylamide and water polymer gel, which is being used successfully in female stress urinary incontinence. We have
assessed the feasibility and effects of a 4 point intra-urethral technique on maximum urethral closing pressure
(MUCP) in male cadavers.
Materials and Methods: Urethral pressure profile
(UPP) was measured twice on 2 male fresh frozen cadaver
models before and after a 4 point injection of 2mls of
Bulkamid® intraurethrally at sphincteric level in 0.5mls aliquots using a 7Fr flexible needle (Olympus 00126).
Results: A clear UPP trace was recordable in both cadavers. The mean MUCP at baseline was 38 cm H2O and the

mean MUCP following Bulkamid® intraurethral injection
was significantly increased to 51.25 cm H2O (P<0.05).
Conclusions: Bulkamid® intraurethral injection in male
cadavers is a simple technique, which significantly increases
MUCP. This raised MUCP may allow for treatment of PPI
and warrants further study in this clinical situation.
P5-12 Autologous rectus fascia pelvic organ
prolapse repair: a mesh free solution for
POP?
Seth J1, Toia B1, Ecclestone H1, Pakzad M1, Hamid R1,
Greenwell T1, Ockrim J1
1University College London Hospital, United Kingdom

Introduction: 40% of women suffer pelvic organ prolapse (POP) in a lifetime. The current standard intervention for vault prolapse is a mesh colposacropexy or
hysteropexy. However, patients and surgeons are increasingly hesitant of the use of mesh given recent UK and FDA
warnings and litigation. A possible alternative is to use
autologous tissue vault support as a mesh free solution.
We report a series of four patients undergoing autologous
POP repair (APOPR) using rectus fascia.
Patients and Methods: 4 patients with a mean age of 53
(38−68) years underwent APOPR between 2014−2016.
All had previous urological/gynecological surgery and
declined standard mesh repairs. All had pre−op videourodynamics and defecating MRI evaluation. Mean follow−up



Table of Contents for the Digital Edition of JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018

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