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Bahr D38, Bycroft J38, Tailor K39, Saleemi A39, Luk A40,
Pearce I40, Steen C41, Alberto M41, Rujancich P41, Olivier
J42, Tay J42, Cannon A42, Coode-Bate J43, Natarajan
M43, Irving S43, Akman J44, Hussain Z44, Murtagh K45,
Carrie A45, Miller M45, Bedi N46, Kavia R46, Malki M47,
Burge F47, Ratan H47, Sadien I48, Miakhil I48, Sharma
S48, Nethercliffe J48, Olaniyi P49, Stammeijer R49, Mason
H49, Symes A49, Lavan L50, Rowbotham C50, Wong C51,
Al-Shakhshir S51, Belal M51, Al-Dhahir W52, Yousif M52,
O'Rourke J52, Tay L53, Ward A53, Parys B53, McKay A54,
Graham J54, Simmons L55, Khadhouri S55, Cottrell A55,
Withington J56, Ajayi L56, Min J57, Evans S57, Liew M58,
Simpson R58, Ross D58, Cumberbatch M59, Pang K59,
Patterson J59, Adams R60, Mirza A60, Acher P60, Tam
J61, Tudor E61, Probert J61, Gallagher M62, Premakumar
Y62, Ager M62, Ayres B62, Kozan A63, Jaffer A63, Din
W63, Biyani C63, Matanhelia M64, Moyles 64, Quinlan D64,
Ness D65, Gowardhan B65, Bateman K66, Wozniak S66,
Clements J67, Hann G67, Gilmore C67, Gray S67, Ellis
G7, Derbyshire L68, Chow K68, Mosey R69, Osman B69,
Kynaston H69, Yassaie O70, Weeratunga G70, Udovicich
C71, O'Connell H71, Lee S72, Hussain A72, Goh M72,
Mbuvi J73, Stewart H73, Samsudin A73, Hughes-Hallet
A6, Rezvani S74, Sheng S74, Husain J74, Kum F75, Symes
R75, Frymann R75, Ahmed I76, Shergill I76, Pickard R5,
Erotocritou P6, Smith D7, Kasivisvanathan V1
1British Urology Researchers in Surgical Training, Department of
Urology, London, United Kingdom, 2University College London, Dept. of
Statistical Science, London, United Kingdom, 3Australian Young Urology
Researchers Organisation (YURO), Australia, 4Information Services
Division, University College London (UCL), United Kingdom, 5Newcastle
University, Dept. of Urology, Newcastle, United Kingdom, 6Whittington
Hospital, Dept. of Urology, London, United Kingdom, 7University
College London Hospital, Dept. of Urology, London, United Kingdom,
8Addenbrooke's Hospital, Cambridge, United Kingdom, 9Austin
Hospital, Heidelberg, Australia, 10Barts Health, Whipps Cross and the
Royal London, London, United Kingdom, 11Bendigo Health, Australia,
12Box Hill Hospital, Melbourne, Australia, 13Broomfield Hospital,
Chelmsford, United Kingdom, 14Charing Cross Hospital, London,
United Kingdom, 15Cheltenham General Hospital, Cheltenham, United
Kingdom, 16Chester Hospital, Mersey, United Kingdom, 17Craigavon
Area Hospital, Northern Ireland, 18Cumberland Infirmary, Carlisle,
United Kingdom, 19Darent Valley Hospital, Dartford, United Kingdom,
20Dorset County Hospital, Dorchester, United Kingdom, 21Edinburgh,
United Kingdom, 22Fiona Stanley Hospital, Western Australia, 23Forth
Valley Royal Hospital, United Kingdom, 24Freeman hospital, Newcastle,
United Kingdom, 25Glasgow Royal Infirmary, United Kingdom, 26Great
Western Hospital, Swindon, United Kingdom, 27Guys Hospital, London,
United Kingdom, 28Princess Alexandra Hospital, Harlow, United
Kingdom, 29Heart of England NHS Foundation Trust, Birmingham,
United Kingdom, 30Heidelberg Repatriation Hospital, Australia,
31High Wycombe Hospital, United Kingdom, 32James Cook University
Hospital, Middlesbrough, United Kingdom, 33James Paget University
Hospital, Great Yarmouth, United Kingdom, 34Kettering General
Hospital, United Kingdom, 35King's College Hospital, London, United
Kingdom, 36Kingston Hospital, Surrey, United Kingdom, 37Leicester
General Hospital, United Kingdom, 38Lister Hospital, Stevenage,
United Kingdom, 39Luton and Dunstable Hospital, United Kingdom,
40Manchester Royal Infirmary, United Kingdom, 41Maroondah
Hospital, Eastern Health, Australia, 42Musgrove Park Hospital,
Taunton, United Kingdom, 43Norfolk and Norwich Hospital, United
Journal of Clinical Urology 11(1S)
Kingdom, 44North Manchester General Hospital, United Kingdom,
45Northampton General Hospital, United Kingdom, 46Northwick
Park / Central Middlesex Hospital, United Kingdom, 47Nottingham
University Hospitals, United Kingdom, 48Peterborough City Hospital,
United Kingdom, 49Princess Royal Hospital, Haywards Heath, United
Kingdom, 50Queen Alexandra Hospital, Portsmouth, United Kingdom,
51Queen Elizabeth Hospital, Birmingham, United Kingdom, 52Queen
Elizabeth Hospital, Kings Lynn, United Kingdom, 53Rotherham
General Hospital, United Kingdom, 54Royal Alexandria Hospital,
Paisley, United Kingdom, 55Royal Devon and Exeter Hospital, United
Kingdom, 56Royal Free Hospital, London, United Kingdom, 57Royal
United Hospitals, Bath, United Kingdom, 58Salford Royal Hospital,
Greater Manchester, United Kingdom, 59Sheffield Teaching Hospital,
United Kingdom, 60Southend University Hospital, United Kingdom,
61Southmead Hospital, Severn, United Kingdom, 62St George's
Hospital, London, United Kingdom, 63St James's University Hospital,
Leeds, United Kingdom, 64St Vincent's University Hospital, Dublin,
Ireland, 65Sunderland Royal Hospital, United Kingdom, 66Torbay
and South Devon NHS Foundation Trust, United Kingdom, 67Ulster
Hospital, Belfast, Northern Ireland, 68University Hospital of South
Manchester, United Kingdom, 69University Hospital Wales, United
Kingdom, 70Wellington Hospital, New Zealand, 71Western Health,
Australia, 72Weston General Hospital, Weston Super Mare, United
Kingdom, 73Whiston Hospital, Merseyside, United Kingdom, 74Wigan
Infirmary, Wigan, United Kingdom, 75Worthing Hospital, Western
Sussex NHS Trust, United Kingdom, 76Wrexham Maelor Hospital,
United Kingdom
Introduction and Objectives: There is conflicting evidence on the role of medical expulsive therapy (MET) in
spontaneous stone passage in acute ureteric colic patients.
However, it is unknown, whether MET has a role in aiding
passage of stones of a particular size or specific ureteric
position. We undertook MIMIC, a multi-centre international cohort study in 71 centres disseminated via a
research collaborative to assess whether MET use
improved rates of SSP adjusting for key confounders.
Methods: Multivariable mixed effects logistic regression
models were created fitted for MET use, age, gender, stone
size and stone position.
To explore the effect of stone size (mm) and stone position (upper, middle and lower ureter) on whether MET
use had an effect on SSP, an interaction term was fitted
between these variables.
Results: 4181 patients were admitted with acute ureteric
colic. 75% (n=3127) were discharged with conservative
management. 80% (n=2516) had a confirmed outcome of
SSP and were included in the multivariable analysis. The
unadjusted odds ratio for the association of MET use with
SSP from univariable analysis was 1.250 (95%CI, 1.041,
1.501). However, following a multivariable mixed effects
logistic regression model, there was no association of MET
use with SSP in any subgroup irrespective of stone size (OR
1.085, 95%CI 0.978, 1.205) or stone position [see Table].
Conclusions: In acute ureteric colic patients who are
suitable for initial conservative management, MET has no
benefit in spontaneous stone passage, regardless of stone
size or position.
Best Academic Paper 2: Table
Table of Contents for the Digital Edition of JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018
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