JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018 - 43

Abstracts

43

P4-5: Table 2. Sensitivity and specificity for PDUR and AD.
Variables
PDUR
0.94
1.58
2.37
AD(mm)
1.5
4.5
7.5

Sensitivity (%)

Specificity (%)

5
67
96

100
65.6
25

1
73
100

100
64.5
25.8

P4-5: Figure 1. PDUR ROC curve.

P4-6 Ureteric stones and acute kidney injury:
What predicts progression?
Sandoval Barba H1, Haque R1, King T1,
Subramonian K1
1Queen Elizabeth Hospital, Birmingham, United Kingdom

Introduction & Objectives: Acute kidney injury (AKI)
in stone-related renal colic is a relative indication for
urgent decompression of the obstructed urinary tract.
Although rare, chronic kidney disease (CKD) may ensue
and we analysed predictors for this progression.
Materials & Methods: Retrospective study of patients
with ureteric stones referred to Urology from the
Emergency Department, who developed AKI within 48
hours of the episode. We analysed stone characteristics
and estimated glomerular filtration rate (eGFR) dynamics
around the clinical event. We compared patients who
recovered from those who developed CKD to find predictors. Wilcoxon and Fisher's exact tests were used.
Results: Out of 522 patients, 49 (9.38%), including 29
men and 20 women with a mean age of 56 years had AKI.
The mean eGFRs at presentation was 41.5 mL/min/1.7
m2 from a baseline of 78.9 mL/min/1.7 m2, and the nadir
was 44.25 mL/min/1.7 m2. Forty-five (91.83%) had hydronephrosis or hydroureter and 16 (32.65%) required
urgent decompression in a median time of 7 (0-19) days.
Five (11.3%) out of the 49 patients developed CKD.
They had higher age (p=0.001) and lower eGFRs at
baseline (p<0.0001), presentation (p<0.0001) and nadir
(p<0.0001) compared to the recovery group. Twenty
patients had kidney abnormalities including hypotrophy,
cystic disease, chronic pyelonephritis or a solitary kidney, of which only the last one (p=0.04) was associated
with CKD.
Conclusion: Most stone-related AKI recover after a
renal colic. Higher age, lower eGFR at baseline, presentation and nadir, as well as a solitary kidney may predict
progression to CKD.
P4-7 Outcomes of elective ureteroscopy
and stone treatment in patients with prior
urosepsis and emergency drainage
Pietropaolo A1, Kyriakides R1, Jones P1, Geraghty R1,
Oliver R1, Somani B K1
1University Hospital Southampton NHS Foundation Trust, United
Kingdom

P4-5: Figure 2. AD ROC curve.

Introduction: Urological guidelines recommend emergency drainage for urosepsis in infected obstructed kidney
secondary to stone disease. However, since the fate of
elective ureteroscopy (URS) in these patients is largely



Table of Contents for the Digital Edition of JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018

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