JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018 - 58
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P6-3 An innovative prostate cancer screening
clinic in the community
Shah J1, Minns S1
Hospitals NHS Foundation Trust, Burton Upon Trent,
Staffordshire, United Kingdom
1Burton
Background: Despite being the most common male cancer, awareness and education around prostate cancer is
poor. Men are also reluctant to seek medical attention and
often present late. We describe the development of and
outcomes of a screening activity within an environment
where men are comfortable: for most men this was at our
local football club, but with the Freemasons, this was at
their lodges and with the African-Caribbean community, at
their community centre.
Methods: We designed a 2-day, pre-booked appointment
only, screening clinic where we took a history, examined
the prostate and undertook a PSA test. Men with abnormal prostate examinations/ high PSA results were invited
for prostate biopsy. All men were invited to complete a
satisfaction survey.
Results: To date, we have held 8 community clinics and
seen 578 asymptomatic men at the local football club, in
their community centre or at a Freemasons lodge. The
average age was 66 years (40-89), average PSA 2.45 (0.145.5) and 65 men had biopsies. To date 32 men have been
diagnosed with prostate cancer and 4 men had metastases
at diagnosis.
A satisfaction survey has consistently shown a response
rate of >85% and most men prefer such clinics in the community rather than at the hospital.
Conclusions: This project has effectively raised awareness of prostate cancer amongst our local community and
engaged men with regards their prostate health, in a comfortable setting. A large number of men have been diagnosed with prostate cancer, highlighting the feasibility of
such community initiatives.
P6-4 Image fusion targeted prostate biopsy
in 740 men at risk: a multicentre evaluation
showing low diagnostic yield of significant
cancer in non-targeted biopsies
Miah S1, Eldred-Evans D2, Shah T1, Hosking-Jervis F2,
Laniado M3, Hindley R3, Doherty A3, Sinclair A3, Burke
D3, Bhardwa J3, Karim O3, Montgomery B3, Bott S3,
Barber N3, Winkler M1, Allen C4, Ahmed H2
1Charing Cross Hospital, London, United Kingdom, 2Imperial College,
London, United Kingdom, 3Nuada Medical, London, United Kingdom,
4University College London Hospital, United Kingdom
Introduction: In this large UK multi-centre, prospective
series, we compared the diagnostic yield of clinically-significant prostate cancer (csPCa) in image-fusion targeted and
non-targeted biopsies.
Journal of Clinical Urology 11(1S)
Patients and Methods: 740 men had transperineal
image-fusion targeted prostate biopsies (MIMSymphony-DXTM) between April 2014 and June 2017
by 11 urologists.
Results: Mean age, median PSA and median prostate volume were 63.2 years, 6.3ng/ml and 43cc respectively.
Overall, 341(46.1%) were diagnosed with csPCa (Gleason
>/=4+3 or any grade >/=6mm) from the 740 men undergoing biopsy. In 378 men undergoing targeted and nontargeted biopsies, 182 (48%) had csPCa. Only 14 men
(3.7%) who underwent both targeted and non-targeted
biopsies were discovered to have csPCa in the non-targeted cores alone. 13 out of these 14 men had a PSA <10.
Of these men 2 had Gleason 4+3=7 disease and the rest
were discovered to have < / = Gleason 3+4 disease.
Insignificant cancer exclusively occurred in non-targeted
prostate cores in 34 men (9%).
Conclusions: In this large multi-centre series, the added
benefit of non-targeted cores is low. An image-fusion targeted-biopsy only has a high detection of csPCa and
reduced over-detection of insignificant cancers.
P6-5 The PRECISION study: Prostate
evaluation for clinically important disease,
sampling using image-guidance or not?
(NCT02380027)
Kasivisvanathan V1, Rannikko A2, Borghi M3,
Panebianco V4, Mynderse L5, Vaarala M6, Briganti
A7, Budäus L8, Hellawell G9, Hindley R10, Roobol
M11, Eggener S12, Ghei M13, Villers A14, Bladou F15,
Villeirs G16, Virdi J17, Boxler S18, Robert G19, Singh P20,
Venderink W21, Hadaschik B22, Ruffion A23, Hu J24,
Margolis D24, Crouzet S25, Klotz L26, Taneja S27, Pinto
P28, Gill I29, Allen C1, Giganti F1, Freeman A1, Morris S1,
Punwani S1, Williams N30, Brew-Graves C30, Takwoingi
Y31, Emberton M1, Moore C1
1University College London and University College Hospital London,
United Kingdom, 2Helsinki University and Helsinki University
Hospital, Finland, 3Centro de Urologia CDU, Argentina, 4Sapienza
University, Italy, 5Mayo Clinic, Rochester, MN, USA, 6University of
Oulu and Oulu University Hospital, Finland, 7San Raffaele Hospital,
Italy, 8Martini Klinik, Germany, 9London North West Healthcare
NHS Trust, UK, 10Hampshire Hospitals NHS Foundation Trust, UK,
11Erasmus University Medical Center, the Netherlands, 12University
of Chicago, USA, 13Whittington Health NHS Trust, UK, 14CHU
Lille, France, 15Jewish General Hospital, Canada, 16Ghent University
Hospital, Belgium, 17Princess Alexandra Hospital NHS Trust,
UK, 18University Hospital Bern, Switzerland, 19Bordeaux Pellegrin
University Hospital, France, 20Royal Free London NHS Foundation
Trust, UK, 21Radboud UMC, the Netherlands, 22University Hospital
Essen, Germany, 23Hospices Civils de Lyon, Centre Hospitalier
Lyon Sud, France, 24Weill Cornell Medicine New York-Presbyterian
Hospital, USA, 25Hospices Civils de Lyon of the Hôpital Edouard
Herriot, France, 26Sunnybrook Health Sciences Centre, Canada,
27New York University Langone Medical Centre, USA, 28National
Institute for Health, Bethesda, USA, 29University Southern California
Table of Contents for the Digital Edition of JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018
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