JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018 - 18

18
muscle, early recurrence and residual disease at early
re-TURBT.
Results: In all, 300 patients underwent WL TURBTs post
'training'. Patient and tumour demographics were similar in
both groups with 85% being NMIBC. Detrusor muscle was
detected in 133/150(88.7%) and 101/150(67.3%) in
PDD-ST and WL-ST, respectively (OR=3.3, 95%CI=2.1-6.9,
p<0.01).The recurrence rate at first check was 11/74(14.9%)
in PDD-ST and 43/68(63.2%) in WL-ST (OR=9.9,
95%CI=4.3-22.0, p<0.01); while 12/49 (24.5%)(PDD-ST)
and 27/63 (43%)(WL-ST) patients had residual cancer at
early re-TURBT (OR=2.3, 95%CI=1.0-5.3, p<0.01).
Conclusion: Prior PDD training within a dedicated list
appears to improve the quality of future white light TURBT.
P1-10 Day case primary transurethral
resection of bladder tumour (TURBT) as
standard protocol in a single UK centre
-should this be the new standard?
Austin T1, Robinson R1, Forshaw C1, Hodgson D1, Hall
S1, Wilby D1
1Urology Department, Portsmouth, United Kingdom

Introduction and Objectives: Transurethral resection
of bladder tumours (TURBT) is an integral component of
the diagnosis, staging and treatment of bladder cancer.
Despite the increasing utilisation of day case surgery in
many areas of surgery, HES data indicates that rates for
TURBT are very low at 9.3 %.
Materials and Methods: A retrospective analysis of all
elective primary TURBTs, Sept '16 to Aug '17, in a single
UK centre was performed. Data were collected on tumour
grade, stage, 30 day readmissions and presence of muscle
in specimen and recurrence at 3 months (surrogates of
resection quality).
Results: 172 were performed, all were included. 130(76%)
male with median age 72 years. 138 (80%) were treated as
a day-case, 11 (6%) had planned admissions, the remaining
23 (14%) were converted to an inpatient admission, the
commonest reason being haematuria. 52% received
Mitomycin-C immediately following the procedure.
30 day re-admission rates were 7.2% and 5.9% and muscle
in specimen rates were 63% and 65% for the day-case and
inpatients groups respectively.
49 (28.5%), 31 (18.0%) and 50 (29.1%) were classified as
low, intermediate and high risk NMIBC respectively. MIBC
was identified in 30 (17.4%) and 12 (7%) did not have
urothelial carcinoma. Recurrence of NMIBC cancer at
three months for patients not receiving adjuvant therapy
occurred in 5 (7%).
Conclusion: This data demonstrates that day case
TURBT is feasible in the majority of patients, has a low
re-admission rate and good oncological outcomes.
Day case TURBT should be considered as standard practice for primary TURBT.

Journal of Clinical Urology 11(1S)
P1-11 10-year experience of RITE
thermochemotherapy for high risk nonmuscle invasive bladder cancer that has failed
BCG
Ayres B1, Backhouse C1, John B1, Thakkar R1, Pulikal
A1, Perry M1, Bailey M1, Issa R1
1St George's Hospital, London, United Kingdom

Introduction: Alternative intravesical treatments have
been tried in patients with high risk non muscle invasive
bladder cancer (NMIBC) who fail BCG. We present our
10-year experience with radiofrequency induced thermochemotherapy (RITE).
Methods: Between October 2006 and August 2017, 135
patients with high risk NMIBC who failed BCG had induction and maintenance RITE thermochemotherapy delivered using Synergo for 1 hour with 40mg mitomycin C.
Data was collected prospectively and Kaplan Meier analysis was performed.
Results: 5 patients (4%) were unable to complete induction treatment due to side effects. Of the remaining 130,
114 (88%) were male and median age was 74 years (IQR
68-80). 82% had CIS with or without papillary tumours. 1-,
5- and 10-year recurrence free survival was 63%, 34% and
24% respectively. 1-, 5- and 10-year progression free survival was 92%, 71% and 62% respectively. Progression to
muscle invasive disease occurred in 11 (8%), prostatic urethral stromal disease in 6 (5%) and metastatic disease in 6
(5%). 8 (6%) developed subsequent upper urinary tract
recurrences. 30 patients (23%) eventually had a cystectomy for their disease. 1- and 5-year overall survival was
98% and 63% respectively. 1- and 5-year cancer specific
survival was 100% and 79% respectively. Median temperature and radiofrequency power did not differ between
those that recurred and those that didn't.
Conclusions: RITE thermochemotherapy has a role in
the management of selected patients with high risk
NMIBC who fail BCG, with a 5-year cancer specific survival rate of 79%.
P1-12 Hyperthermic intravesical
chemotherapy using the combat BRS system
for BCG-unresponsive non-muscle invasive
bladder cancer - A multicentre study
Ashton A1, de Jong J2, Hendricksen K3, Rosier M2,
Boormans J2, Mostafid H4
1St Richard's Hospital, Chichester, United Kingdom, 2Erasmus
MC Cancer Institute, Rotterdam, Netherlands, 3Netherlands
Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam,
Netherlands, 4Royal Surrey County Hospital, Guildford, United
Kingdom

Objectives: Adjuvant intravesical instillations with bacillus Calmette-Guérin (BCG) is the recommended treatment option for patients with intermediate and high-risk



Table of Contents for the Digital Edition of JCU - Abstracts of the BAUS 2018 Scientific Meeting - June 2018

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