Multiple Sclerosis Journal - October 2017 - 1548

Multiple Sclerosis Journal 23(11)
Table 2. Mean scores (SD) of the primary and secondary outcome measures at each measurement moment.
Baseline

Primary outcomes
CIS20r fatigue (8-56)a
IPA indoors (0-4)a
IPA family role (0-4)a
IPA outdoors (0-4)a
IPA social relations (0-4)a
IPA work and education (0-4)a
Secondary outcomes
FSS (1-7)a
MFIS total (0-84)a
MFIS physical (0-36) a
MFIS cognitive (0-40)a
MFIS psychosocial (0-8)a
CIS20r total (20-140)a
CIS20r concentration (5-35)a
CIS20r motivation (4-28)a
CIS20r physical activity (3-21)a
SF36 vitality (0-100)
SF36 physical functioning (0-100)
SF36 bodily pain (0-100)
SF36 general health (0-100)
SF36 physical role functioning (0-100)
SF36 emotional role functioning (0-100)
SF36 social functioning (0-100)
SF36 mental health (0-100)
RAP communication (0-4)a
RAP mobility (0-15)a

T8

T16

T26

T52

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

Mean (SD)

n

CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control

42.9 (8.5)
44.2 (6.0)
0.9 (0.5)
0.7 (0.6)
1.4 (0.7)
1.5 (0.7)
1.8 (0.6)
1.7 (0.7)
1.1 (0.6)
1.0 (0.6)
2.2 (0.8)
1.9 (0.8)

44
46
44
46
44
46
44
46
44
46
37
42

33.5 (10.4)
41.0 (8.3)
0.7 (0.5)
0.7 (0.6)
1.3 (0.5)
1.4 (0.7)
1.5 (0.5)
1.6 (0.6)
1.1 (0.5)
1.0 (0.5)
1.8 (0.9)
1.9 (0.8)

38
38
38
38
38
38
38
38
38
38
35
34

34.0 (11.2)
40.3 (8.2)
0.7 (0.6)
0.8 (0.6)
1.3 (0.7)
1.4 (0.7)
1.4 (0.6)
1.5 (0.5)
1.1 (0.5)
0.9 (0.5)
2.0 (0.8)
1.9 (0.9)

39
35
38
36
38
36
38
35
38
36
34
34

36.9 (12.1)
40.9 (7.8)
0.9 (0.5)
0.8 (0.6)
1.3 (0.6)
1.5 (0.7)
1.4 (0.6)
1.6 (0.6)
1.1 (0.5)
1.0 (0.5)
1.8 (0.7)
2.0 (0.8)

39
36
39
35
39
35
39
35
39
35
34
31

38.9 (9.7)
39.5 (9.0)
0.8 (0.5)
0.7 (0.6)
1.3 (0.6)
1.5 (0.7)
1.5 (0.6)
1.5 (0.6)
1.0 (0.5)
1.0 (0.5)
1.9 (0.9)
1.9 (0.8)

39
35
39
36
39
36
39
36
39
36
35
30

CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control
CBT
Control

5.4 (0.7)
5.5 (0.8)
47.3 (12.5)
47.7 (9.6)
21.6 (5.7)
22.5 (5.0)
21.5 (7.8)
20.8 (6.2)
4.3 (1.6)
4.3 (1.4)
94.4 (19.4)
94.6 (13.8)
22.7 (8.5)
22.1 (6.6)
15.5 (6.3)
15.1 (4.9)
13.4 (5.6)
13.2 (3.6)
42.3 (13.4)
40.4 (14.7)
55.8 (22.1)
62.2 (20.4)
68.8 (17.5)
66.7 (20.2)
49.5 (12.6)
53.8 (14.5)
20.5 (31.6)
16.3 (28.5)
60.6 (41.5)
67.4 (41.9)
61.1 (18.5)
61.7 (18.9)
64.5 (13.5)
68.8 (12.6)
2.9 (0.9)
2.7 (0.8)
10.9 (2.9)
10.1 (2.7)

44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
44
46
43
45
41
45

4.7 (0.9)
5.3 (0.9)
38.3 (15.0)
44.3 (14.2)
17.4 (6.4)
20.8 (6.2)
17.6 (8.7)
19.6 (8.5)
3.3 (1.9)
4.0 (1.8)
77.0 (23.3)
90.0 (16.4)
20.0 (8.1)
21.3 (6.2)
13.2 (5.8)
15.2 (5.1)
10.3 (4.9)
12.4 (3.6)
54.2 (16.6)
43.7 (14.4)
58.8 (21.5)
57.0 (23.3)
74.2 (17.6)
69.9 (20.50
46.1 (13.6)
51.3 (13.6)
49.3 (40.9)
23.7 (32.9)
82.5 (32.6)
71.1 (42.6)
70.7 (18.7)
69.1 (18.1)
73.8 (12.1)
71.4 (13.6)
2.8 (1.0)
2.5 (0.8)
10.2 (2.8)
10.0 (2.5)

38
37
38
36
38
36
38
36
38
36
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
38
41
42
40
40

4.5 (1.1)
5.2 (0.7)
38.7 (16.4)
41.2 (11.9)
17.8 (7.3)
19.6 (6.3)
17.4 (8.8)
18.1 (7.3)
3.4 (1.8)
3.4 (1.3)
78.5 (24.6)
83.6 (22.9)
20.1 (7.6)
21.3 (7.3)
13.9 (6.4)
15.1 (5.0)
10.5 (5.3)
12.4 (4.3)
53.2 (17.2)
45.4 (12.3)
58.2 (24.8)
61.3 (20.1)
73.3 (19.7)
68.6 (21.3)
46.5 (16.2)
48.2 (13.4)
48.0 (40.1)
32.4 (35.5)
74.8 (36.3)
72.2 (39.4)
68.9 (21.0)
74.3 (16.8)
71.7 (12.4)
71.7 (13.9)
2.9 (0.7)
2.5 (0.6)
10.7 (2.9)
10.5 (3.2)

38
36
38
36
38
36
38
36
38
36
39
36
39
36
39
36
39
36
37
36
37
35
37
36
37
36
37
36
37
36
37
35
37
36
41
42
41
42

4.9 (1.0)
5.3 (0.7)
40.9 (16.5)
41.7 (13.5)
19.5 (8.1)
19.4 (6.3)
17.7 (8.5)
18.7 (7.6)
3.7 (1.9)
3.6 (1.5)
84.2 (24.8)
88.1 (19.0)
20.8 (7.4)
20.0 (6.5)
14.9 (6.3)
15.6 (5.8)
11.6 (4.7)
11.6 (4.6)
50.9 (19.0)
45.6 (13.5)
55.8 (23.7)
58.1 (21.7)
67.6 (20.5)
67.2 (22.9)
48.6 (13.1)
49.2 (14.5)
42.9 (46.2)
27.8 (38.2)
76.1 (40.4)
73.1 (39.7)
70.8 (22.1)
71.9 (17.5)
72.9 (13.7)
71.0 (16.8)
2.9 (0.9)
2.6 (0.8)
10.7 (3.0)
10.6 (2.5)

39
34
39
34
39
34
39
34
39
34
39
36
39
36
39
36
39
36
39
36
39
36
39
36
39
36
39
36
39
36
39
36
39
36
40
38
39
38

5.0 (0.9)
5.1 (0.9)
42.5 (12.2)
39.1 (13.8)
20.3 (6.1)
18.1 (6.8)
18.6 (7.3)
17.6 (7.4)
3.6 (1.6)
3.4 (1.6)
87.5 (20.8)
86.3 (21.2)
20.8 (7.0)
20.4 (8.0)
14.8 (6.1)
14.2 (5.1)
12.9 (5.0)
12.1 (4.4)
46.9 (16.6)
46.2 (17.1)
55.9 (22.3)
60.3 (22.0)
70.4 (20.7)
70.5 (24.6)
48.6 (15.3)
50.3 (15.3)
28.8 (37.4)
38.5 (39.4)
71.8 (36.3)
71.2 (42.4)
67.7 (19.0)
73.6 (20.6)
68.3 (15.4)
71.1 (16.1)
2.7 (0.7)
2.7 (0.9)
11.5 (3.0)
10.7 (2.9)

39
37
39
37
39
37
39
37
39
37
39
35
39
35
39
35
39
35
39
37
39
37
39
37
39
37
39
37
39
37
39
37
39
37
39
39
39
38

(Continued)

1548

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Table of Contents for the Digital Edition of Multiple Sclerosis Journal - October 2017
