ISSN 1352-4585 | http://journals.sagepub.com/home/msj VO LU M E 2 3 | NU MBE R 1 1 | OCTOBE R 2 0 1 7 MULTIPLE SCLEROSIS JOURNAL Formerly Multiple Sclerosis ® Editorial * Aerobic exercise, cognitive behavioural therapy and energy conservation management for Multiple Sclerosis (MS) fatigue: Are three trials better than one? Topical Review * Science is 1% inspiration and 99% biomarkers Controversies in MS * Advanced MRI measures like DTI or fMRI should be outcome measures in future clinical trials Original Articles * Translocator positron-emission tomography and magnetic resonance spectroscopic imaging of brain glial cell activation in multiple sclerosis * Infection-related health care utilization among people with and without multiple sclerosis * Primary progressive multiple sclerosis presenting with severe predominant cognitive impairment and psychiatric symptoms: A challenging casehttp://journals.sagepub.com/home/msj