Tumori Journal Abstract Book - October 2020 - 86

86	
Bafunno D.1, Romito F.2, Cormio C.2, Minoia C.2, Loseto G.2, Dellino
M.2, Opinto G.2, Silvestris E.2, Guarini A.2, Giotta F.2, Catino A.2,
Montrone M.2, Pizzutilo P.2, Longo V.2, Mastrandrea A.2, Ricci D.2,
Pesola F.2, Galetta D.2
1

IRCCS Istituto Tumori "Giovanni Paolo II", Bari; 2IRCCS Istituto Tumori
"Giovanni Paolo II", Bari

Background: The psychological impact of the lockdown experienced during the COVID-19 pandemic has
been found detrimental for the general population, but it
has still not been evaluated in cancer patients. We have
investigated the psychological status of outpatients
receiving anti-neoplastic treatmentduring the lockdown
in a non-COVID Cancer Center, with the following
aims: to measure the levels of post-traumatic stress
symptoms, depression and anxiety, to compare patients
with different diagnosis. An additional aim was to offer
a psychological on-line support to patients who need it.
Material and methods: Outpatients attending the
IRCCS "Giovanni Paolo II" in Bari for their therapy
were asked to complete these questionnaires: The
Hospital Anxiety and Depression Scale (HADs) and the
Impact of Event Scale-Revised (IES-r).Worries regarding the COVID-19 on patients' lives, socio-demographic
and clinical details were investigated using a brief structured questionnaire.
Results: One-hundred seventy-six outpatients (n.59 with
lung cancer, n.40 with breast cancer, n.77 with lymphoma)
were enrolled. Mean age was 57.9 y.o. (SD ±14); 48%
were male. We found that 54,4% of patients were above
the cut-off (score⩾16) for HADS general scale. The
mean-IES-R score of patients was 25 (SD±17), with
22.8% indicating severe level of PTDS. The HADS-D has
been found significantly correlated with IES-R (r= 0.35;
p<0.005). The 70% of patients declared that their worries
have increased during the pandemic; their bigger concerns were: the risk of getting infected while at hospital
(51.4%); the risk of infecting relatives coming back home
(38.7%), andthe risk of delaying therapy (35.3%).When
comparing the level of anxiety and depression in different
diagnosis it has been found that patients with lung cancer
have higher distress(HADs-general scale) than patients
with lymphoma (F=17.3, p<0.005) and breast cancer
(F=8.86, p<0.005).
Conclusions: This study focused on the psychological
aspects of cancer patients during the COVID-19 pandemic, finding that one quarter of patients has severe
post-traumatic stress symptoms, and has psychological
distress. Patients with lung cancer have higher distress
compared to the other groups. This condition risks being
overlooked by clinical concerns, so weunderline the
importance to place even more attention to the psychological needs of patients, especially for those who have
symptoms similar to COVID-19 as in lung cancer, in
order to offer adequate support.

Tumori Journal 106(2S)

D41
SHORT-TERM MORTALITY AMONG
CANCER PATIENTS WITH SUSPECTED
OR ASCERTAINED COVID INFECTION
Fusco V.1, Alessio M.2, Rossi M.1, Zai S.1, Piovano P.L.1, Traverso E.1,
Blengio F.1, Vincenti M.1, Guglielmini P.F.1, Bellotti G.1, Manfredi R.1,
De Martino I.2, Numico G.1
1

S.C. Oncologia - Azienda Ospedaliera Ss. Antonio e Biagio e C.Arrigo, Alessandria;
IRFI - Azienda Ospedaliera Ss. Antonio e Biagio e C.Arrigo, Alessandria

2

Background: SARS-2 (COVID-19) infection is recent.
Mortality among cancer patients affected by Covid-19 is
unknown.
Patients and methods: Since February till to May 2020, we
observed cancer patients with ascertained or suspected Covid
infection (all symptomatic, or admitted in hospital due to
undetermined pneumonia infection). Patients were classified
in three subpopulations: a) patients resulted as Covid positive
at the first pharyngeal swab; b) patients positive at swab other
than first (ie, the second or third one); c) patients with a clinical scenario compatible with Covid infection but with negative swab, or never tested before death We reviewed clinical
trajectory and rate of deaths classified as Covid-linked.
Results: We observed 27 possible Covid cases among cancer patients. Sex: 12 M/15 F. Type of cancer: lung in 9,
colon in 6, breast in 4, others in 8. The patients were in diagnostic phase (5), under adjuvant treatment (2), on advanced
disease therapy (16), in advanced disease not under active
treatment (4). Out of 27 patients, 14 resulted as Covid positive at the first pharyngeal swab (group a); 3 were positive at
swab other than first (ie, the second or third one)(group b);
10 patients with a clinical scenario compatible with Covid
infection but with at least one negative swab (9) or never
tested (1) (group c). On 20th May 2020,12 patients are alive,
and 15 patients are dead: 9 with ascertained Covid (positive
pharyngeal swab) and 6 without Covid confirmation. In the
three subpopulations: a) Seven patients died and 4 patients
are alive with negativized swab. b) All 3 patients are alive
with negativized swab. c) Out of 10 patients with a clinical
scenario compatible with Covid infection but not ascertained infection, 7 patients died within the observation time
(death attributed to probable Covid infection even in absence
of positive swab) and 3 are under observation.
Conclusions: Preliminary data show a high mortality rate
(15 out of 27; 55.5%) among cancer patients with ascertained Covid infection but also in cancer patients with suspected infection and severe symptoms.

D42
SARS-CoV-2 screening and
monitoring in cancer patients:
Azienda Usl Toscana Centro
Oncology Department experience



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
Tumori Journal Abstract Book - October 2020 - 1
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Tumori Journal Abstract Book - October 2020 - Cover3
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