Tumori Journal Abstract Book - October 2020 - 85

D - COVID-19	

85

Luigi Gonzaga Hospital, Orbassano, Torino, Italy; 4 Department of Oncology,
University of Turin, San Luigi Gonzaga Hospital, Orbassano, Torino, Italy;
UOC Oncologia Medica B, Università degli Studi di Roma, Sapienza,
Policlinico Umberto I; Roma; Italy5 Department of Oncology, University of
Turin, San Luigi Gonzaga Hospital, Orbassano, Torino, Italy

Background: At the end of 2019, a novel viral pneumonia,
caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), was described in China. Since then, Italy
has soon become one of the most affected countries. In this
challenging situation, the oncological community was called
to protect cancer patients (pts), especially those affected by
lung cancer, considered one of the most vulnerable population due to older age, multiple comorbidities and type of
infection. This study aimed to investigate the clinical management of NSCLC pts, in order to provide a reliable picture
of real-word practice during the COVID-19 outbreak.
Materials and Methods: A 29-questions survey focusing
on the clinical management and therapeutic indications for
NSCLC pts during COVID-19 pandemic was sent to 95
medical/thoracic oncologists across different Italian regions.
Results: From April 12th to May 2nd, 79 responses were
received, with an overall response rate of 83%. The majority
(77.3%) of oncologists declared a significant change in the
outpatient management of NSCLC pts. The number of consultations in case of suspected NSCLC decreased in about
half of cases (46.8%), with a major reduction when considering the number of pts coming from the emergency department for a first oncological evaluation (60% of cases). The
total number of pts with any stage, newly diagnosed NSCLC,
within the observational period, was reported to be lower
than the pre-pandemic era by the 56% of oncologists. For pts
candidates to adjuvant chemotherapy and concurrent chemoradiation, the therapeutic indications followed guidelines in
62% and 72% of cases, respectively. As regards the metastatic disease, the majority of oncologists confirmed their
clinical indication to first-line treatment. The collected data
revealed major changes in the second line therapeutic
options, most related to timing and schedules of administration. Lung cancer pts' accrual in clinical trials dramatically
has fallen for 79% of oncologists and follow-up consultations were mostly managed by telemedicine.
Conclusions: This survey showed that Italian oncologists
are determined to follow the available guidelines for the
clinical management of NSCLC pts during this emergency
time, while more complicate is to deal with clinical trials.
In this tough landscape, telemedicine provides a valid support to facilitate patient-healthcare interactions.

D39
Impact of COVID-19 outbreak on
cancer patient care in a Lombardy
outpatient clinic
1

1

2

1

Quaquarini E. , Saltalamacchia G. , Caldana G. , Presti D. , Mollica
L.1, Balletti E.1, Teragni C.1, Biscaldi E.2, Frascaroli M.2, Palumbo R.1,
Bernardo A.1, Sottotetti F.1

1
ICS Maugeri IRCCS, UO Oncologia Medica, Pavia; 2ICS Maugeri IRCCS, UO
Oncologia Traslazionale, Pavia

Background: Coronavirus disease 2019 (COVID-19) is a
respiratory tract infection that was first recognized in
China at the end of December 2019, later becoming pandemic. Lombardy was among the first areas to have an outbreak of COVID-19 outside China. Oncology societies
have been quick to issue guidelines on cancer care during
the pandemic, suggesting telemedicine services, reducing
clinic visits, switching to subcutaneous or oral therapies,
when possible, evaluating the benefit of each treatment.
We investigated the management of cancer patients in an
outpatient clinic of Pavia, Lombardy, during COVID-19
outbreak.
Patients and methods: Using our electronic databases,
we evaluated the number of patients accessing to hospital
for anticancer drug infusion from 24th February 2020 to
30th April 2020 taking into account for each patient: diagnosis, line of treatment, reason of a therapy delay, and city
of residence. We than compared the data with the same
period of the year 2019 and 2018.
Starting from 24th February 2020, caregivers were not
admitted to the hospital. Patient were asked to wear mask
and gloves; outside the hospital, body temperature was
measured and a questionnaire asking for influential symptoms and possible COVID-19 contacts was performed.
The day before the visit, a phone call was performed with
the discussion of patient clinical conditions and possible
symptoms of COVID-19. Patients performed also blood
exams. Patients complaining suspected symptoms or having had contact with a COVID-19 positive person were
asked to call their doctor of general medicine and not
access to hospital for therapy. All healthcare personnel
started to wear mask, caps, disposable overall and gloves.
Results: A total of 2552 visits for drug infusion were recorded
in 2020 compared to 2728 in 2019 and 2674 in 2018. In 2020,
36% of patients received treatment for an early stage disease
and 64% for a metastatic tumour; 66% of patients came from
Pavia and province, 3% from Lodi and province, 14% from
Milan and province, 5% from other Lombardy provinces and
12% from other regions; 63 patients delayed the visit: 40%
for "pandemic fear", 32% for travel restrictions, 16% for toxicity and 12% for worsening of clinical conditions. A total of
7 COVID-19 positive patient occurred.
Conclusions: The prompt adoption of personal protective
equipment and controlled access to the hospital may have
helped to reduce COVID-19 infections allowing the correct continuation of cancer treatments.

D40
Psychological distress in
outpatients with lymphoma, lung
and breast cancer during COVID-19
pandemic



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
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