Tumori Journal Abstract Book - October 2020 - 69

D - COVID-19	
management aspects of the emergency COVID19 as sent
to Piedmont and Valle d'Aosta health workers in oncology
on April 7th 2020.
Results: 201 questionnaires were completed: 60% oncologists, 33% nurses, 7% palliativists; 41% <45y; 33% university hospital, 32% non-university hospital 32% ASL. 91%
considered the pre-triage model and COVID questionnaire
as essential for identifying suspected patients. Structures
were converted for assistance of COVID patients in 76% of
cases and 26% of the health workers accepted a role
change:18% on voluntary basis, while only 24% believe to
have received adequate training. On clinical activity, significant reduction (48%) was registered only for first visits
(CAS) while interdisciplinary discussions (GIC) have been
maintained although with alternative modalities
(remotely,77%). 88% of follow-up visits were remotely
conducted. Considering relational aspects, discomfort
mainly concerned absence of physical contact and forms of
non-verbal communication hampered by the PPE, increased
communication time. However, healthcare provider-patient
relationship has not changed (20%), even allowing a more
transparent and empathic interaction despite the use of alternative means of communication. Health professionals suffered the lack of a reference in the management of the
pandemic and/or guidelines of behavior and specific skills.
Major concern was the lack of PPE and the fear to be a
source of infection for one's family (in 67% of cases a physical distancing from one's family nucleus was carried out or
would have been desired). 52% operators report they have
not yet received the swab test; in case of swab test, this was
carried out due to presence of symptoms (8%) or intermediate-high risk due to prolonged contact with a COVID case,
with 60% believing times and procedures were inadequate.
Conclusions: This picture is a precious benchmark to face
with in order to reorganize the oncological activity in the
immediate future, taking great account of the perception
and experience of oncology operators. Submitted on behalf
of the AIOM Piemonte & Valle d'Aosta Regional Board

D09
Results of a national survey
exploring the perception and
attitudes of Italian physicians
towards the management
of checkpoint inhibitors in
oncology during COVID-19
outbreak
Tagliamento M.1, Spagnolo F.1, Poggio F.1, Soldato D.2, Conte B.1,
Ruelle T.1, Barisione E.3, De Maria A.4, Del Mastro L.5, Di Maio M.6,
Lambertini M.7
1

IRCCS Ospedale Policlinico San Martino, Oncologia Medica 2, Genova;
IRCCS Ospedale Policlinico San Martino, Clinica di Oncologia Medica,
Genova; 3IRCCS Ospedale Policlinico San Martino, Pneumologia Interventistica,
Genova; 4Università di Genova e IRCCS Ospedale Policlinico San Martino,

2

69
Malattie Infettive, Genova; 5Università di Genova e IRCCS Ospedale Policlinico
San Martino, Breast Unit, Genova; 6Università di Torino e Ospedale Ordine
Mauriziano, SCDU Oncologia, Torino; 7Università di Genova e IRCCS
Ospedale Policlinico San Martino, Clinica di Oncologia Medica, Genova

Background: During the COVID-19 outbreak oncological
care has been reorganized to face the emergency. Cancer
patients have been reported to be at higher risk of severe
events related to SARS-CoV-2. Moreover, there are concerns of a possible interference between immune checkpoint
inhibitors (ICIs) and the pathogenesis of the infection.
Material and Methods: A 22-item questionnaire was
shared with Italian physicians managing ICIs, between May
6 and 16, 2020. This survey aimed at exploring the perception about SARS-CoV-2 related risks in cancer patients
receiving ICIs, and whether the management of these
patients has been modified during COVID-19 outbreak.
Results: Respondents were 104, with a median age of 35.5
years, mainly females (58.7%), mainly working in Northern
Italy (71.2%). 47.1% of respondents were afraid that a synergism could exist between ICIs mechanism of action and
SARS-CoV-2 pathogenesis, leading to worse outcomes.
97.1% of respondents would not deny an ICI only for the
possible occurrence of COVID-19. Measures for reducing
hospital visits have been adopted by choosing the ICIs
schedule with fewer administrations, adopting the highest
labeled dose of each drug (55.8%) and/or choosing, among
different ICIs for the same indication, the one with the
longer interval between cycles (30.8%). 53.8% of respondents suggested the need to test for SARS-CoV-2 every cancer patient candidate to ICIs. Regarding the differential
diagnosis between immune-related adverse events (irAEs)
and COVID-19 manifestations, 71.2% of respondents
declared to manage a patient with onset of dyspnea and
cough like a COVID-19 patient until otherwise proven (ie,
waiting for the result of SARS-CoV-2 test before doing
other diagnostic or therapeutic procedures), while the same
management has been applied only by the 28.8% of respondents when dealing with a patient with onset of diarrhea;
however, 96.2% did not reduce the use of steroids to manage irAEs during the pandemic. No major impact of
COVID-19 on physicians' attitudes towards the use of ICIs
to manage specific clinical situations in different cancer
types (ie, lung, breast, melanoma, urothelial) was observed.
Conclusions: These results highlight the uncertainty of
physicians dealing with ICIs in cancer patients during
COVID-19 outbreak, supporting the need of dedicated
studies on this regard.

D10
"DOMONCOVID PROJECT": AN
INNOVATIVE HOMECARE MODEL
FOR CANCER PATIENTS DURING THE
PANDEMIC ERA



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
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