Tumori Journal Abstract Book - October 2020 - 68

68	
immunoassay for the detection of IgG and IgM antibodies to
SARS-CoV-2. The aim of the study was to evaluate antiSARS-CoV-2 seroconversion rate in patients with cancer and
healthcare professionals with confirmed or clinically suspected COVID-19.
Results: Between March 30 and May 11, 2020, 166 subjects
were enrolled in the study. Cancer patients and health workers were 61 (36.7%) and 105 (63.3%), respectively. Seventyfour subjects (44.6%) had confirmed SARS-CoV-2 diagnosis
by RT-PCR testing on nasopharyngeal swab specimen, while
49 (29.5%) had a clinical suspicious of COVID-19 in
absence of RT-PCR confirmation. Median time between
symptom onset/ RT-PCR confirmation to serum antibody
test was 17 days (IQR, 26). Considering the population with
confirmation by RT-PCR, 83.8% was IgG positive. Neither
differences in terms of IgG positivity rate nor in median time
from SARS-CoV-2 diagnosis to IgG detection were observed
between cancer patients and health workers (87.9% vs
80.5%; P=0.39; 23.0 vs 28.0 days; P=0.21).
Conclusions: Our data indicate that SARS-CoV-2-specific
IgG antibody detection does not differ between cancer
patients and healthy subjects. Fast test for antibody detection
can be complementary to RNA RT-PCR testing for the diagnosis of COVID-19 in this vulnerable patient population.

D07
The emotional impact of COVID-19
outbreak on cancer out-patients
and their caregivers: results of a
survey in the heart of the Italian
pandemic
Cona M.S.1, Dalu D.1, Rota S.1, Ferrario S.1, Gambaro A.R.1, Tosca
N.1, Filipazzi V.1, La Verde N.1
1
ASST Fatebenefratelli Sacco - Polo Ospedaliero Luigi Sacco - Department of
Oncology, Milan

Background: Cancer patients (pts) during COVID-19 pandemic have to be protected because of higher morbidity and
mortality risk. While follow up visits were rescheduled,
frequently treatments couldn't be delayed without compromising efficacy. During pandemic, lockdown laws were
approved and people were encouraged stay home. The aim
of this study is to investigate the emotional discomfort of
pts and their caregivers (CG), who need to access to Day
Hospital to receive cancer treatment during pandemic.
Materials and methods: This is a single-institutional
experience of the Department of Oncology at Luigi Sacco
Hospital, one of the most involved Italian hospitals by
COVID-19 pandemic. From 5 May to 5 June 2020 we have
conducted a survey on out-pts in active cancer therapy and
their CG. We have set up 2 different multiple choice questionnaires (15 questions for pts and 17 for CG) enquiring
demographic characteristic and changes in emotional status, interpersonal relationships with health professionals

Tumori Journal 106(2S)
(HCPs) and self-perception of treatments outcomes. The
answers could be yes, enough, no and I don't know; yes and
enough were put together for data analysis.
Results: 625 pts and 254 CG questionnaires were examined. 65.1% pts and 56.3% CG were female; 69.8% pts
were >60 ys while 50.4% CG were 41-60ys old. 40.1% of
the pts vs only 25.6% CG think to be at greater risk of contagion because live together or access to the hospital. Both
pts and CG consider containment measures (triage at the
entrance, social distancing, personal protective equipment)
a valid support to avoid the spread of infection (86.3% vs
85.4% respectively) without excessive loss of time (78.2%
vs 88.6%). Waiting and performing visits and treatments
without CG have no impact on emotional status of pts
(64.4%), but generate in CG greater anxiety (58.8%) and
fear of a bad home pts management (19.8%). The majority
of pts (53.9%) and CG (39.4%) thinks pandemic doesn't
influence treatments outcome. Relationships with HCPs
was not negatively affected for 73.1% pts and 66.6% CG.
Conclusions: The majority of pts believes to have an
higher risk of contagion therefore approves the application
of safety standards, that help them feel more protected.
Moreover, good relationship with HCPs contributed to
face treatments without additional distress. For CG the
main trouble is limitations which don't allow to fully share
the pts's care route and the perceive an impairment in
HCPs relationship.

D08
Covid-19 emergency: survey by the
regional AIOM group for health
workers in oncology in Piedmont
and Valle d'Aosta
Spadi R.1, Bironzo P.2, Vavala' T.3, Boglione A.4, Buosi R.5, Bustreo
S.1, Carnio S.2, Fanchini L.1, Pignataro D.2, Saggia C.6, Sirotova' Z.7,
Tucci M.8, Traverso E.9, Buffoni L.10
1

SC Oncologia 1, AOU Città della Salute e della Scienza di Torino, Torino;
Dipartimento di Oncologia, Università degli Studi di Torino, AOU S. Luigi
Gonzaga, Orbassano, Torino; 3SC Oncologia ASL CN1, Ospedale Ss. Annunziata
Di Savigliano, Savigliano, Cuneo; 4SC Oncologia Ospedale San Giovanni Bosco,
Torino; 5SC Oncologia - ASL-AL- Sede Ospedale S. Spirito Casale M.TO,
Casale Monferrato, Alessandria; 6Oncologia AOU "Maggiore della Carità" di
Novara, Novara; 7Oncologia ed Ematologia Oncologica. Azienda USL della
Valle d'Aosta, Aosta; 8Oncologia Ospedale Cardinal Massaia ASL AT, Asti; 9SC
Oncologia Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo Alessandria,
Alessandria; 10SC Oncologia Medica Humanitas Gradenigo, Torino
2

Background: Dimension and speed of the COVID19
health emergency forced pressing reorganization of the
hospital machine with foreseeable repercussions on both
cancer patients and healthcare professionals. A survey to
the latter had the aim to describe oncology reaction at the
time of Coronavirus spread in Piedmont and Valle d'Aosta.
Material and methods: An electronic survey containing
questions regarding the organizational, relational and



Tumori Journal Abstract Book - October 2020

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Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
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