Tumori Journal Abstract Book - October 2020 - 210

210	

Tumori Journal 106(2S)

Activities

March April

May

Triage A*
Triage B*
N° of suspicious case
N° of suspicious cases not admitted
N° nasopharyngeal swabs performed
N° surgical procedures performed
N° outpatient chemotherapies
N° pts. transferred due to Covid-19
N° triage hours

5976
=
41
24
461
195
2676
1
1318

12517
9616
71
9
917
359
2502
=
1912

8862
3902
125
55
986
339
2702
1
1581

*N° of checked individuals

U11
Activity of a Phase I Clinical Unit
during the COVID-19 pandemic
Sabatelli P.1, D'Ausilio T.1, Marsele P.1, De Pasquale F.1, Bevilacqua
S.1, Florio M.1, Di Napoli A.2, Palazzo I.2, Morrone L.1, Perrone F.1,
Schettino C.1, Gravina A.1
1

S.C. Sperimentazioni Cliniche - Istituto Nazionale Tumori IRCCS Fondazione
G. Pascale, Napoli; 2S.C. Farmacia Ospedaliera - Istituto Nazionale Tumori
IRCCS Fondazione G. Pascale, Napoli

Background: Enrolment of patients in phase 1 trials is a
difficult task everywhere and at every time. It is reported
that on average less than one patient per month is enrolled
worldwide in phase 1 trials. COVID-19 pandemic has
been a further problem during 2020, with many trials
closed by the sponsors for logistic reasons and for the fear
of causing a fatal infection in cancer patients.
Materials and methods: We reviewed the activity of our
phase 1 unit in terms of enrolment of new patients during six
months, three before and three during COVID-19 pandemia,
and of treatment of patients enrolled before the pandemic.
Results: Out of 8 trials active at our unit, only one did not
close the possibility of enrolling new patients during the pandemic. No treatment was stopped because of the pandemic.
During the pandemic we enrolled three new patients in the
only one open trial. The same number of new patients had
been enrolled during the previous three months. In addition,
three further patients were pre-screened during the pandemic
resulting not eligible. Operatively, an intensive strategy of
testing healthcare workers (nurses, doctors, study coordinators, biologists) with blood testing for anti-COVID19 IgM
and IgG, and pharyngeal and nasal swabs was applied. In
addition, patients were managed with a triage protocol that
similarly included blood testing at each access and swab testing in case of IgM/IgG presence. Overall, no one of the
health coworkers resulted positive to blood or swap testing
and only one patients was positive to IgM testing, with negative swap and subsequently negative blood testing, possibly
representing a false positive case. Sanitization of phase 1
rooms was also performed regularly, once per week or more
frequently at need in case of patients or health workers resulting positive to blood testing.

Conclusions: Our phase 1 unit was able to maintain the
same level of activity during the pandemic, thanks to one
trial that was not suspended by the sponsor and this goal
was reached thanks to organization and preventive measures set up by the Institutional dedicated professionals.
Overall, a good result was achieved in terms of safety of
both patients and healthcare workers.

U12
Staying at home in the COVID-19
pandemic: The perspective of
people living with cancer
participating at the AIIAO survey
Biagioli V.1, Belloni S.2, Albanesi B.1, Piredda A.3, Caruso R.4
1
Sapienza University, Rome; 2Tor Vergata University, Rome; 3European
Institute of Oncology, Milan; 4IRCCS Policlinico San Donato, Milan

Background: During phase 1 of the COVID-19 emergency, all Italian citizens had to quarantine at home to
reduce the transmission of the virus. People living with
cancer were considered at higher risk for infection and
severe events. Moreover, they had to face several challenges in accessing healthcare services, especially those
travelling to receive cancer care. Therefore, it is important
to get a complete picture of the cancer experience during
the lockdown from the patient perspective.
Material and Methods: An online survey was conducted
from March 29th to May 3rd, 2020. Italian cancer patients
were invited to participate while they were staying at home
because of the COVID-19 pandemic. Data about their
socio-demographic and clinical characteristics, the perception of self-isolation (ISOLA scale), the measures they
adopted to reduce their infectious risk, and beliefs about
the impact of the pandemic on their disease were collected.
The study was approved by the scientific committee of the
Italian Association of Cancer Nurses (AIIAO).
Results: Overall, 195 adult people living with cancer completed the survey. They were mainly women (76%), with a
mean age of 50.3 years (SD=11.2), diagnosed with haematological malignancy (51.3%), and at home in self-isolation
for more than 6 weeks (39.5%). Most of them never/rarely
(80.4%) left their house, except for their health (49.7%) and
going to the supermarket (50.3%). About 54% believed to
be at higher risk for COVID-19 infection and 51% for complications. To prevent COVID-19 infection, 29% of them
used some remedies to boost their immune system. Those
who experienced most social problems in quarantine were
the older ones, with lower education, and living without
children. About 29% of participants reported that their cancer was not under control, as 24% reported that their frequency of going to the hospital had diminished and 38%
were not going to the hospital at all during the pandemic.
Conclusions: The COVID-19 pandemic and the lockdown
had a significant impact on cancer patients' lives. Living



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
Tumori Journal Abstract Book - October 2020 - 1
Tumori Journal Abstract Book - October 2020 - 2
Tumori Journal Abstract Book - October 2020 - 3
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Tumori Journal Abstract Book - October 2020 - Cover3
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