Tumori Journal Abstract Book - October 2020 - 186

186	
Results: The questionnaire was completed by 280 male
and 310 female pts (70.3%). Median age was 66 years
(range 28-86). Discontinuation occurred for medical indication or toxicity in the majority of pts; forgetfulness in
9,8% of cases. A significant difference in compliance was
observed in male/female. Waste occurred in 247 cycles. A
total of 6004 tablets were discarded for all causes, with a
total priced of € 53.284.
Conclusions: with an estimated waste of € 151.588 per
year, oral chemotherapy represents a significant financial
burden to society. A system that will allow safe and efficient recycling of drugs from pts who no longer need them
to those who do, should be a desirable medically sound
solution. Health care practitioners sensibility and support
of establishing pharmacies is mandatory to prevent wastage and to recycle discarded drugs.

T20
Perception of sexuality disorders
in cancer patients among health
providers: a survey from Rete
Oncologica del Piemonte e della
Valle d'Aosta
Sperti E.1, Caristo T.2, Terzolo S.1, Varese P.3, Di Maio M.1, Bertetto
O.2, Numico G.4
1

AOU Mauriziano Umberto I, Torino; 2Dipartimento Rete Oncologica del
Piemonte e della Valle d'Aosta, Torino; 3Ospedale Civile Ovada, Ovada; 4AO
SS Antonio e Biagio e Cesare Arrigo, Alessandria

Background: Disorders of the sexual sphere in cancer
patients are very frequent (40-100%), but they are underestimated in clinical practice. ASCO guidelines recommend that the health care team introduce a discussion with
the patient, regarding sexual health.
Material and methods: The study group "Supportive
Care" of the Rete Oncologica del Piemonte e della Valle
d'Aosta sent a survey to physicians and nurses of the oncology, hematology and radiotherapy departments of the network. There were 11 questions to understand perception of
the problem, degree of preparation of the operators, and
presence of structural, cultural, or emotional obstacles for
the management of the disorders. Subgroup analysis was
performed by profession, gender and age.
Results: Between June and September 2019, 315 people
replied: 77% women, 53% nurses, 70% >39y. In a range
from 1 to 10, median score of how much sexual disorders
have an impact on quality of life was 7, and median score of
how much they are taken into consideration was 5.
Physicians and nurses believe that attention to sexual disorders are their own duty in 89% and 81% respectively, without significant differences in subgroup analysis. To the
question "how often do you talk with patients about sexual
disorders" 12,7% answered "never" and 45.5% answered

Tumori Journal 106(2S)
"rarely", with a significant difference between physicians
and nurses (never or rarely 60% vs 74% respectively, p =
0.0001). In 45.5% of cases is the issue is introduced by the
patient. Main obstacles to deal with this topic (not mutually
exclusive) were insufficient preparation (59.05%), embarrassment (51.4%), and lack of time (28.5%). Subgroup analysis revealed a greater concern for the lack of time by
physicians than nurses (p = 0.0001) and by > 39 years than
younger respondents (p = 0.0015); and a greater concern
for embarrassment by women than men (p = 0.04). The
self-evaluation of preparation for the management of female
and male sexual disorders was "nothing" / "a little" in 18.7%
/ 65.7% and 29.1% / 56.5% respectively. 67.6% of respondents declared the absence of availability of a counselling
about sexual disorders.
Conclusions: This survey highlighted a high perception
and interest for sexual disfunction in cancer patients. Lack
of preparation and time, or embarrassment, prevent an
adequate management of the problem. There is a clear
need for training, both in terms of knowledge of the problems and treatments, and in terms of communication.

T21
Correlation between
haematological, immunological
and odontostomatologic
parameters and clinical outcome
in cancer patients with bone
metastasis: a single center
experience
Deiana M.1, Lai E.2, Ziranu P.2, Pretta A.3, Impera V.3, Liscia N.3,
Mariani S.2, Tolu S.3, Camera S.3, Persano M.2, Donisi C.2, Spanu
D.2, Saba G.2, Dubois M.2, Migliari M.2, Massa E.2, Demurtas L.2,
Madeddu C.2, Dettori C.4, Astara G.2, Scartozzi M.2
1
Department of Medical Sciences and Public Health, Occupational Health
Section, University of Cagliari, Monserrato, Italy; Medical Oncology Unit,
University Hospital and University of Cagliari, Cagliari, Italy, Cagliari; 2Medical
Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy,
Cagliari; 3Medical Oncology Unit, Sapienza University of Rome-University Hospital
and University of Cagliari, Cagliari, Italy, Cagliari; 4Department of Conservative
Dentistry and Endodontics, University of Cagliari, Cagliari, Italy, Cagliari

Background: Monocytes (M)/lymphocytes (L) ratio
(MLR), neutrophils (N)/L ratio (NLR) and platelets (P)/L
ratio (PLR), interleukin 6 (IL-6) and tumour necrosis factor alpha (TNF-α) are cancer inflammation biomarkers.
Bone metastasis (BM) are common in advanced cancer
patients (pts) and might induce skeletal-related events
(SREs), compromising survival and quality of life. Bone
target therapy (BTT) delays SREs occurrence but it may
lead to odontostomatologic toxicity, thus requiring preliminary oral examination.
Material (Patients) and Methods: We retrospectively
collected baseline MLR, NLR, PLR, pro-inflammatory



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
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