Tumori Journal Abstract Book - October 2020 - 169

S - Management of Cancer Pain	
74.3% in Arm DEX4 (95%CI, -11.1% to 16.5%). No significant differences were observed between groups in proportions of patients who reported no impact on daily life
due to nausea, vomiting, or both during the 5-day observation period after cisplatin administration.
Conclusions: Since efficacy results were comparable
between the two DEX-sparing regimens in this study, we
conclude that the simplified three-drug regimen with
NEPA plus single-dose DEX is an option that is not associated with significant reduction in anti-emetic control during the 5-day period or an impact on patient functioning in
the setting of cisplatin.

S04
Another hospital admission
through the emergency room?
Looking for a fragility pattern
in advanced cancer patients: an
update
Velutti L.1, Saetta A.2, Giordano L.2, Marinello A.2, Cammarota A.2,
Grimaudo M.S.2, Digiacomo N.2, Cullia L.3, Villa E.2, Lopane D.4,
Provasoli C.2, Poggio C.5, Giuffrè S.2, Pavesi C.2, Rimassa L.6, Santoro A.6
1
Unità di Oncologia Medica e Unità di Cure Palliative Domiciliari, Humanitas
Clinical and Research Center IRCCS, Rozzano, Milano; 2Humanitas Clinical
and Research Center IRCCS, Rozzano, Milano; 3Cooperativa Servizi
alla Persona CSAP, Bergamo; 4Cooperativa Sociale 9Coop, Romano di
Lombardia, Bergamo; 5Fondazione Insieme con Humanitas, Rozzano, Milano;
6
Humanitas Clinical and Research Center IRCCS and Humanitas University,
Rozzano, Milano

Background: Cancer patients (pts) are often treated with
specific therapies even in the last period of clinical history. It is common to observe an intensification of care,
hospitalization, diagnostic procedures in the last months
of life. These pts are more likely to experience hospitalization due to toxicity, worsening, clinical conditions, concomitant non-oncologic diseases, disease progression.
They often access palliative care program (PCP) at a very
advanced stage of the disease, or never access it at all. It
is common to observe that these pts are hospitalized after
an admission from emergency room (ER). This is frequently the moment when a PCP is proposed and activated, or when the pts die.
Methods: We made a retrospective analysis of pts admitted from ER in our oncologic ward. We evaluated: pts'
characteristics, histology, diagnosis' date, metastases'
sites, comorbidities, previous anticancer therapies (CT)
and radiotherapy (RT) for advanced disease, invasive and
or higt-cost procedures, previous ER access, admissions
for supportive care (SC), transfusions, artificial nutrition,
use of high-cost antibiotics, in last 90 days. Pts were
divided into two fragility groups: less-fragile (LF), candidate to CT or follow-up, and more-fragile (MF), candidate
to a PCP or who died.

169
Results: From August 2017 to July 2018 we recorded 908
admissions, 535 from ER (58.9%) in 450 pts, 85 pts had
more than 1 admission. Pts were: women/men 223/227,
the median age was 65.4 years. The pts in 2 fragility groups
were: LF/MF 248/202. The differences found were: age ⩾
65 years in 45.9% of pts in LF group, 55.4% in MF group,
p=0.046; visceral metastases' sites in 70.3% of pts in LF,
84.8% in MF, p<0.001; ⩾1 lines of CT in 62.5% of pts in
LF, 80.7% in MF, p<0.001; ⩾1 RT treatments in 22% of
pts in LF, 32% in MF, p=0.023; previous admissions for
SC in 45.5% of pts in LF, 61.8% in MF, p<0.001; previous
admissions for SC in last 90 days in 21.2% of pts in LF,
38.1% in MF, p=0.004; ER accesses in last 90 days in
38.3% of pts in LF, 63.8% in MF, p<0.001. We find no
other differences.
Conclusions: We identified a MF profile: pts with ⩾65
years, with visceral metastases' sites, who did ⩾1 lines of
CT, ⩾1 RT treatments, with ⩾1 prior admission for SC, =1
admission for supportive care and =1 ER access in the last
90 days. This fragility profile may help oncologists timely
offer a PCP to advanced stage pts. This could prevent some
ER access and admissions close to the end-of-life.

S05
Home-based management of
cancer patients experiencing
toxicities: how a nurse-led
telephone triage (NTT) may impact
on lung cancer patients (LCPs)
hospitalizations
Calvetti L.1, Marta T.2, Cimenton R.2, Gentile A.2, Pretto R.2, Pavan
M.2, Toniolo A.2, Valente C.2, Fusa C.2, Gasparin B.2, Pagiusco G.2,
Simionato F.2, De Vivo R.2, Merlini L.2, Aprile G.2
1

Oncologia Ospedale San Bortolo, AULSS8 Berica, Vicenza, Padova;
Oncologia Ospedale San Bortolo, AULSS8 Berica, Vicenza

2

Background: Novel organization models are needed to
ensure early management of new treatment-related toxicity of anticancer treatments, especially in LCPs. Aim of
this prospective observational study was to evaluate the
impact of the introduction of NTT in reducing hospitalizations of cancer patients on treatment.
Methods: Cancer patients on active medical treatment at
the Department of Oncology of San Bortolo Hospital
(Vicenza, Italy) were given instructions to refer to NTT
in case of treatment-related adverse events (TRAEs). The
service was opened Mon to Fri from 8am to 8pm.
Assessment of TRAEs was performed by trained oncology nurses according to the CTCAE scale and subsequent
actions were taken according to the severity of the events.
The assessment was performed made under the supervision of a medical oncologist in charge of the service
while on duty. Co-Primary endpoints were to compare



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
Tumori Journal Abstract Book - October 2020 - 1
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