Tumori Journal Abstract Book - October 2020 - 151

H - Genitourinary Tumours	
Patients Aand Methods: We conducted a retrospective
analysis of 200 pts with mPC treated at Modena Cancer
Center between 2003 and 2019. Pts were divided into two
groups according to median age of the whole group (young
<72 years and elderly ⩾72 years). Differences between
groups were investigated with χ2 test. Overall survival
(OS) and progression free survival (PFS) curves were
drawn using the Kaplan-Meier method and log-rank test
was used to compare OS and PFS within age groups.
Results: Among all pts, 58,1% had Gleason Score⩾ 8 and
46,4% were stage IV at initial diagnosis. Among pts without evidence of metastasis at diagnosis median time for
mPC was 69,3 months (mo). 59.3% of pts received prostatectomy. Median OS (mOS) of all pts was 47 mo (95%CI,
41,7-190,9). Median follow up was 37,7 mo. Young group
included 92 pts (46%). These pts had higher initial stage
(IV: 57,1% vs 36,8%, p=0,007), similar BMI (=25: 66% vs
62%, p=ns), Gleason score (=8: 57,8% vs 58,4%, p=ns)
and T stage distribution (p=ns) compared to elderly pts.
There was a trend of less bone metastasis at mPC diagnosis (57,1% vs 71,6%, p=0,059) and more lymph-node
involvement (51,2% vs 39,7%, p=ns) in this group. They
received more docetaxel as I line treatment (52,2% vs
31,5%, p=0,003) and more lines of therapy than others (=3
lines: 44,6% vs 29,6%, p=0,029). There was a statistically
significant difference in OS between the two groups: mOS
was 59 mo (95%CI, 43,0-190,9) in young group and 41,7
mo (95%CI, 33,2-50,4) in elderly group, p=0,0019. No
significant difference in term of PFS in I, II, II and IV lines
of therapy (PFS1, PFS2, PSF3 and PFS4) was evidenced
between the two groups, but higher PFS5 was seen in
young group (8,2 vs 2,1 mo, p=0,0418). It was underlined
that only few pts both young and elderly received IV and
V lines of therapy (23-18 and 10-5, respectively).
Conclusions: To our best knowledge, this is the first analysis that takes into consideration the impact of age on the
clinical outcome of patients treated with new drugs in a
real word setting. Younger patients with mPC seem to have
a better OS statistically significant compared with old
patients but our data are limited for the retrospective nature
of the study.

H27
A single center experience of
multidisciplinary team (MDT):
improving care of patients with
prostate cancer
Ermacora P.1, Zattoni F.2, Girometti R.3, Povolato M.4, Toso F.3,
Pizzolitto S.5, Delneri C.6, Vescini F.7, Barban F.8, Moretti E.9,
Romanin M.10, Garattini S.K.11, Trovò M.10, Dal Moro F.2, Fasola
G.11, Magli A.10
1
Dipartimento di Oncologia, Azienda Sanitaria Universitaria Friuli Centrale,
Udine; 2Clinica Urologica, Azienda Sanitaria Universitaria Friuli Centrale,

151
Presidio Ospedaliero di Udine, Udine; 3Dipartimento di Radiodiagnostica,
Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero di
Udine, Udine; 4Medicina Nucleare, Azienda Sanitaria Universitaria Friuli
Centrale, Presidio Ospedaliero di Udine, Udine; 5Anatomia Patologica,
Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero di
Udine, Udine; 6Istituto di Medicina Fisica e Riabilitazione Gervasutta,
Azienda Sanitaria Universitaria Friuli Centrale, Udine; 7Endocrinologia e
Malattie del Metabolismo, Azienda Sanitaria Universitaria Friuli Centrale,
Presidio Ospedaliero di Udine, Udine; 8Associazione Cure Palliative Mirko
Špacapan - Amore per sempre Onlus; ASUFC - Day Hospital Oncologico,
Dipartimento di Oncologia di Udine, Udine; 9Fisica Sanitaria, Azienda
Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero di Udine, Udine;
10
Radioterapia, Azienda Sanitaria Universitaria Friuli Centrale, Presidio
Ospedaliero di Udine, Udine; 11Dipartimento di Oncologia, Azienda Sanitaria
Universitaria Friuli Centrale, Presidio Ospedaliero di Udine, Udine

Background: The heterogeneity of treatment of prostate
cancer often results in controversies. Therefore, coordination of care is needed to assure best clinical practice and
high quality performances. For all these reasons, a MDT
approach to prostate cancer has been implemented at
ASU-FC since June 2019 This report describes the methodology and the initial experience of our external ISO9001
certifier approved MDT.
Material and methods: Each member of MDT drafted its
own reference treatment guidelines on a matrix. The most
used were from Italian Association of Medical Oncology
(AIOM) and European Association of Urology (EAU).
Agreement on standards, as for protocol of service, were
developed for each professional area (e.g. radiological
diagnosis within 15 days for mpRM and 30 days for abdomen CT and total body bone scan, final histological diagnosis within 20 days, start of either surgery or radiotherapy
in less than 45 days for high risk patients as well as less
than 120 days for low risk cancers). The process indicators
(managerial, diagnostic and quality of life-related) individuated in the light of local health care system availability
were: reduction of time to reach diagnosis, improvement
of adherence to guidelines for optimization of resources,
improvement of biopsy sampling to facilitate histological
reports, increase of the number of patients under active
surveillance and research improvement. Finally, a specific
evaluation system related to the general, operational and
specific ISO9001-2015 accreditation requirements was
developed to assess the starting level and elaborate an
"action plan for improvement".
Results: Methodology phase was started on March 2019
defining the structures involved in the core team (oncology
radiotherapy, urology, medical oncology, radiology and
nuclear medicine) along with the non-core ones (pathology, bone health endocrinology, physiatry, psychology and
medical physics). Bi-weekly meetings produced a specific
flow diagram for each disease stage and a histology reporting system shared with physicians. From September,
MDTs were initiated leading to medical reviews shared on
the Hospital computer system. Finally, an external audit
resulted into ISO9001-2015 certification.



Tumori Journal Abstract Book - October 2020

Table of Contents for the Digital Edition of Tumori Journal Abstract Book - October 2020

Contents
Tumori Journal Abstract Book - October 2020 - Cover1
Tumori Journal Abstract Book - October 2020 - Cover2
Tumori Journal Abstract Book - October 2020 - I
Tumori Journal Abstract Book - October 2020 - II
Tumori Journal Abstract Book - October 2020 - Contents
Tumori Journal Abstract Book - October 2020 - IV
Tumori Journal Abstract Book - October 2020 - V
Tumori Journal Abstract Book - October 2020 - 1
Tumori Journal Abstract Book - October 2020 - 2
Tumori Journal Abstract Book - October 2020 - 3
Tumori Journal Abstract Book - October 2020 - 4
Tumori Journal Abstract Book - October 2020 - 5
Tumori Journal Abstract Book - October 2020 - 6
Tumori Journal Abstract Book - October 2020 - 7
Tumori Journal Abstract Book - October 2020 - 8
Tumori Journal Abstract Book - October 2020 - 9
Tumori Journal Abstract Book - October 2020 - 10
Tumori Journal Abstract Book - October 2020 - 11
Tumori Journal Abstract Book - October 2020 - 12
Tumori Journal Abstract Book - October 2020 - 13
Tumori Journal Abstract Book - October 2020 - 14
Tumori Journal Abstract Book - October 2020 - 15
Tumori Journal Abstract Book - October 2020 - 16
Tumori Journal Abstract Book - October 2020 - 17
Tumori Journal Abstract Book - October 2020 - 18
Tumori Journal Abstract Book - October 2020 - 19
Tumori Journal Abstract Book - October 2020 - 20
Tumori Journal Abstract Book - October 2020 - 21
Tumori Journal Abstract Book - October 2020 - 22
Tumori Journal Abstract Book - October 2020 - 23
Tumori Journal Abstract Book - October 2020 - 24
Tumori Journal Abstract Book - October 2020 - 25
Tumori Journal Abstract Book - October 2020 - 26
Tumori Journal Abstract Book - October 2020 - 27
Tumori Journal Abstract Book - October 2020 - 28
Tumori Journal Abstract Book - October 2020 - 29
Tumori Journal Abstract Book - October 2020 - 30
Tumori Journal Abstract Book - October 2020 - 31
Tumori Journal Abstract Book - October 2020 - 32
Tumori Journal Abstract Book - October 2020 - 33
Tumori Journal Abstract Book - October 2020 - 34
Tumori Journal Abstract Book - October 2020 - 35
Tumori Journal Abstract Book - October 2020 - 36
Tumori Journal Abstract Book - October 2020 - 37
Tumori Journal Abstract Book - October 2020 - 38
Tumori Journal Abstract Book - October 2020 - 39
Tumori Journal Abstract Book - October 2020 - 40
Tumori Journal Abstract Book - October 2020 - 41
Tumori Journal Abstract Book - October 2020 - 42
Tumori Journal Abstract Book - October 2020 - 43
Tumori Journal Abstract Book - October 2020 - 44
Tumori Journal Abstract Book - October 2020 - 45
Tumori Journal Abstract Book - October 2020 - 46
Tumori Journal Abstract Book - October 2020 - 47
Tumori Journal Abstract Book - October 2020 - 48
Tumori Journal Abstract Book - October 2020 - 49
Tumori Journal Abstract Book - October 2020 - 50
Tumori Journal Abstract Book - October 2020 - 51
Tumori Journal Abstract Book - October 2020 - 52
Tumori Journal Abstract Book - October 2020 - 53
Tumori Journal Abstract Book - October 2020 - 54
Tumori Journal Abstract Book - October 2020 - 55
Tumori Journal Abstract Book - October 2020 - 56
Tumori Journal Abstract Book - October 2020 - 57
Tumori Journal Abstract Book - October 2020 - 58
Tumori Journal Abstract Book - October 2020 - 59
Tumori Journal Abstract Book - October 2020 - 60
Tumori Journal Abstract Book - October 2020 - 61
Tumori Journal Abstract Book - October 2020 - 62
Tumori Journal Abstract Book - October 2020 - 63
Tumori Journal Abstract Book - October 2020 - 64
Tumori Journal Abstract Book - October 2020 - 65
Tumori Journal Abstract Book - October 2020 - 66
Tumori Journal Abstract Book - October 2020 - 67
Tumori Journal Abstract Book - October 2020 - 68
Tumori Journal Abstract Book - October 2020 - 69
Tumori Journal Abstract Book - October 2020 - 70
Tumori Journal Abstract Book - October 2020 - 71
Tumori Journal Abstract Book - October 2020 - 72
Tumori Journal Abstract Book - October 2020 - 73
Tumori Journal Abstract Book - October 2020 - 74
Tumori Journal Abstract Book - October 2020 - 75
Tumori Journal Abstract Book - October 2020 - 76
Tumori Journal Abstract Book - October 2020 - 77
Tumori Journal Abstract Book - October 2020 - 78
Tumori Journal Abstract Book - October 2020 - 79
Tumori Journal Abstract Book - October 2020 - 80
Tumori Journal Abstract Book - October 2020 - 81
Tumori Journal Abstract Book - October 2020 - 82
Tumori Journal Abstract Book - October 2020 - 83
Tumori Journal Abstract Book - October 2020 - 84
Tumori Journal Abstract Book - October 2020 - 85
Tumori Journal Abstract Book - October 2020 - 86
Tumori Journal Abstract Book - October 2020 - 87
Tumori Journal Abstract Book - October 2020 - 88
Tumori Journal Abstract Book - October 2020 - 89
Tumori Journal Abstract Book - October 2020 - 90
Tumori Journal Abstract Book - October 2020 - 91
Tumori Journal Abstract Book - October 2020 - 92
Tumori Journal Abstract Book - October 2020 - 93
Tumori Journal Abstract Book - October 2020 - 94
Tumori Journal Abstract Book - October 2020 - 95
Tumori Journal Abstract Book - October 2020 - 96
Tumori Journal Abstract Book - October 2020 - 97
Tumori Journal Abstract Book - October 2020 - 98
Tumori Journal Abstract Book - October 2020 - 99
Tumori Journal Abstract Book - October 2020 - 100
Tumori Journal Abstract Book - October 2020 - 101
Tumori Journal Abstract Book - October 2020 - 102
Tumori Journal Abstract Book - October 2020 - 103
Tumori Journal Abstract Book - October 2020 - 104
Tumori Journal Abstract Book - October 2020 - 105
Tumori Journal Abstract Book - October 2020 - 106
Tumori Journal Abstract Book - October 2020 - 107
Tumori Journal Abstract Book - October 2020 - 108
Tumori Journal Abstract Book - October 2020 - 109
Tumori Journal Abstract Book - October 2020 - 110
Tumori Journal Abstract Book - October 2020 - 111
Tumori Journal Abstract Book - October 2020 - 112
Tumori Journal Abstract Book - October 2020 - 113
Tumori Journal Abstract Book - October 2020 - 114
Tumori Journal Abstract Book - October 2020 - 115
Tumori Journal Abstract Book - October 2020 - 116
Tumori Journal Abstract Book - October 2020 - 117
Tumori Journal Abstract Book - October 2020 - 118
Tumori Journal Abstract Book - October 2020 - 119
Tumori Journal Abstract Book - October 2020 - 120
Tumori Journal Abstract Book - October 2020 - 121
Tumori Journal Abstract Book - October 2020 - 122
Tumori Journal Abstract Book - October 2020 - 123
Tumori Journal Abstract Book - October 2020 - 124
Tumori Journal Abstract Book - October 2020 - 125
Tumori Journal Abstract Book - October 2020 - 126
Tumori Journal Abstract Book - October 2020 - 127
Tumori Journal Abstract Book - October 2020 - 128
Tumori Journal Abstract Book - October 2020 - 129
Tumori Journal Abstract Book - October 2020 - 130
Tumori Journal Abstract Book - October 2020 - 131
Tumori Journal Abstract Book - October 2020 - 132
Tumori Journal Abstract Book - October 2020 - 133
Tumori Journal Abstract Book - October 2020 - 134
Tumori Journal Abstract Book - October 2020 - 135
Tumori Journal Abstract Book - October 2020 - 136
Tumori Journal Abstract Book - October 2020 - 137
Tumori Journal Abstract Book - October 2020 - 138
Tumori Journal Abstract Book - October 2020 - 139
Tumori Journal Abstract Book - October 2020 - 140
Tumori Journal Abstract Book - October 2020 - 141
Tumori Journal Abstract Book - October 2020 - 142
Tumori Journal Abstract Book - October 2020 - 143
Tumori Journal Abstract Book - October 2020 - 144
Tumori Journal Abstract Book - October 2020 - 145
Tumori Journal Abstract Book - October 2020 - 146
Tumori Journal Abstract Book - October 2020 - 147
Tumori Journal Abstract Book - October 2020 - 148
Tumori Journal Abstract Book - October 2020 - 149
Tumori Journal Abstract Book - October 2020 - 150
Tumori Journal Abstract Book - October 2020 - 151
Tumori Journal Abstract Book - October 2020 - 152
Tumori Journal Abstract Book - October 2020 - 153
Tumori Journal Abstract Book - October 2020 - 154
Tumori Journal Abstract Book - October 2020 - 155
Tumori Journal Abstract Book - October 2020 - 156
Tumori Journal Abstract Book - October 2020 - 157
Tumori Journal Abstract Book - October 2020 - 158
Tumori Journal Abstract Book - October 2020 - 159
Tumori Journal Abstract Book - October 2020 - 160
Tumori Journal Abstract Book - October 2020 - 161
Tumori Journal Abstract Book - October 2020 - 162
Tumori Journal Abstract Book - October 2020 - 163
Tumori Journal Abstract Book - October 2020 - 164
Tumori Journal Abstract Book - October 2020 - 165
Tumori Journal Abstract Book - October 2020 - 166
Tumori Journal Abstract Book - October 2020 - 167
Tumori Journal Abstract Book - October 2020 - 168
Tumori Journal Abstract Book - October 2020 - 169
Tumori Journal Abstract Book - October 2020 - 170
Tumori Journal Abstract Book - October 2020 - 171
Tumori Journal Abstract Book - October 2020 - 172
Tumori Journal Abstract Book - October 2020 - 173
Tumori Journal Abstract Book - October 2020 - 174
Tumori Journal Abstract Book - October 2020 - 175
Tumori Journal Abstract Book - October 2020 - 176
Tumori Journal Abstract Book - October 2020 - 177
Tumori Journal Abstract Book - October 2020 - 178
Tumori Journal Abstract Book - October 2020 - 179
Tumori Journal Abstract Book - October 2020 - 180
Tumori Journal Abstract Book - October 2020 - 181
Tumori Journal Abstract Book - October 2020 - 182
Tumori Journal Abstract Book - October 2020 - 183
Tumori Journal Abstract Book - October 2020 - 184
Tumori Journal Abstract Book - October 2020 - 185
Tumori Journal Abstract Book - October 2020 - 186
Tumori Journal Abstract Book - October 2020 - 187
Tumori Journal Abstract Book - October 2020 - 188
Tumori Journal Abstract Book - October 2020 - 189
Tumori Journal Abstract Book - October 2020 - 190
Tumori Journal Abstract Book - October 2020 - 191
Tumori Journal Abstract Book - October 2020 - 192
Tumori Journal Abstract Book - October 2020 - 193
Tumori Journal Abstract Book - October 2020 - 194
Tumori Journal Abstract Book - October 2020 - 195
Tumori Journal Abstract Book - October 2020 - 196
Tumori Journal Abstract Book - October 2020 - 197
Tumori Journal Abstract Book - October 2020 - 198
Tumori Journal Abstract Book - October 2020 - 199
Tumori Journal Abstract Book - October 2020 - 200
Tumori Journal Abstract Book - October 2020 - 201
Tumori Journal Abstract Book - October 2020 - 202
Tumori Journal Abstract Book - October 2020 - 203
Tumori Journal Abstract Book - October 2020 - 204
Tumori Journal Abstract Book - October 2020 - 205
Tumori Journal Abstract Book - October 2020 - 206
Tumori Journal Abstract Book - October 2020 - 207
Tumori Journal Abstract Book - October 2020 - 208
Tumori Journal Abstract Book - October 2020 - 209
Tumori Journal Abstract Book - October 2020 - 210
Tumori Journal Abstract Book - October 2020 - 211
Tumori Journal Abstract Book - October 2020 - 212
Tumori Journal Abstract Book - October 2020 - 213
Tumori Journal Abstract Book - October 2020 - 214
Tumori Journal Abstract Book - October 2020 - 215
Tumori Journal Abstract Book - October 2020 - 216
Tumori Journal Abstract Book - October 2020 - 217
Tumori Journal Abstract Book - October 2020 - 218
Tumori Journal Abstract Book - October 2020 - 219
Tumori Journal Abstract Book - October 2020 - 220
Tumori Journal Abstract Book - October 2020 - 221
Tumori Journal Abstract Book - October 2020 - 222
Tumori Journal Abstract Book - October 2020 - 223
Tumori Journal Abstract Book - October 2020 - 224
Tumori Journal Abstract Book - October 2020 - 225
Tumori Journal Abstract Book - October 2020 - 226
Tumori Journal Abstract Book - October 2020 - 227
Tumori Journal Abstract Book - October 2020 - 228
Tumori Journal Abstract Book - October 2020 - 229
Tumori Journal Abstract Book - October 2020 - 230
Tumori Journal Abstract Book - October 2020 - 231
Tumori Journal Abstract Book - October 2020 - 232
Tumori Journal Abstract Book - October 2020 - 233
Tumori Journal Abstract Book - October 2020 - 234
Tumori Journal Abstract Book - October 2020 - 235
Tumori Journal Abstract Book - October 2020 - Cover3
Tumori Journal Abstract Book - October 2020 - Cover4
https://www.nxtbookmedia.com