JCU - January 2022 - 28

28
Journal of Clinical Urology 15(1)
Table 2. Postoperative surgical and functional outcomes.
Number
Surgical outcomes
Median inpatient stay (days)
Transfusions rate
Complications CD <3
Complications CD >3
Delayed complication rate
Bladder neck stenosis requiring single incision
Submeatal stricture: dilated
Submeatal stricture: dilated and long-term intermittent self-catheterisation
Incisonal hernia: repaired
Urethral stricture requiring urethroplasty
Urethral stricture requiring single incision
Functional outcomes
Erectile dysfunction completed data
Full erectile dysfunction
Partial erectile dysfunction
Potent
Continence completed data
Continent
Minor stress leakage
1 Pad
>1 Pad
Appliance
Artificial urethral sphincter inserted
Discussion
The present study aims advance the discussion regarding
high-risk Cap by documenting the surgical, functional and
oncological outcomes of the largest contemporary UK
series of pathological T3, T3b, T4 and N1 patients following
primary surgery. Traditionally, surgery has been discouraged
in these patients,10 despite data demonstrating
similar outcomes in patients with high-risk CaP when
compared to surgery for lower risk disease.14
Complication rates are often under-reported or lack a
standardised classification in this area.20 Rates of 3-30%
have been reported following surgery for high-risk
533
452
65
16
532
243
182
50
40
17
3
79.6%
85%
12.2%
3%
79.5%
45.6%
34.2%
9.4%
7.5%
3.2%
0.4%
disease.25 The present study found a 30-day mortality rate of
zero, a median inpatient stay of one day (1-17 days) and a
transfusion rate of 0.6%. The minor complication rate was
5.8%, with 1.6% experiencing a major complication
(Clavian-Dindo ⩾3) and 1.8% experiencing a delayed surgical
complication. Aning et al. recently reported on highrisk
CaP data from the national BAUS registry of UK
surgeon-reported outcomes, and found similar inpatient
stays (one day), transfusion rates (<1%) and significant
complication rates (2%).20 In a potentially more comparable
series of high and very high-risk CaP patients (NCCN), Koo
et al. actually reported a major complication rate of 8-12%.26
Therefore, these data are in line with similar reported series.
1 (range 1−17)
4
39
11
11
1
3
1
2
1
3
0.6%
5.8%
1.6%
1.8%
0.1%
0.4%
0.1%
0.3%
0.1%
0.4%
Percentage

JCU - January 2022

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JCU - January 2022 - Cover3
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