54 European Stroke Journal 8(1S) Figure 1. Primary stroke centers (centers for IVT) and secondary stroke centers (centers for IVT and ET). Figure 2. Application for stroke prenotification. system before arrival. Part of pre-hospital management was also a change of the patient's delivery to the hospital. Before, the EMS used to bring patients to an emergency department or neurology department. The delivery of a stroke patient directly to CT became the standard in most hospitals. The only problem with the application is that due to the GDPR (General Data Protection Regulation), the patient identification data cannot be entered into the application. Still, the doctor must call the EMS crew during transport to the treating hospital so it does not affect the overall transport time. The application enables the GPS location of the ambulance to be monitored so that the stroke team can prepare for the arrival of the patient accordingly. The application is also used in communication between primary and secondary centers. The neurologist does a physical examination, history data check before non-contrast CT, and CT angiography is mandatory in all hospitals. A radiologist and neurologist immediately interpret the CT. If the patient meets the criteria for thrombolysis, the alteplase bolus is administered on the CT table, and then IVT continues, or it starts at the stroke unit when the distance is very short.