Laboratory Animals - June Issue - 258

258

Laboratory Animals 53(3)

Abstract
Die intestinale Mikrobiota kann wichtige, weitreichende Auswirkungen auf ihren jeweiligen Wirt haben. Bisher
waren Versuchstiere, insbesondere Ma
¨use, das wichtigste Studiensystem fu
¨r die Mikrobiota-Forschung. Es
wird allerdings inzwischen zunehmend klarer, dass Versuchstiere oft nur unzureichend Aspekte der Biologie
von Wildtieren modellieren, und dies gilt auch fu
¨ r die Untersuchung der intestinalen Mikrobiota. Die vorliegende Abhandlung bietet eine Besprechung der relativ geringen Zahl von Studien u
¨ber die Mikrobiota von
wilden Nagern, einschließlich einer kritischen Einscha
¨tzung der Unterschiede zwischen der intestinalen
Mikrobiota von Labor- und wildlebenden Nagern. Schließlich werden die vielen potenziellen Vorteile und
Chancen von Wildtiersystemen fu
¨r die Erforschung der intestinalen Mikrobiota betrachtet.

Resumen
La microbiota intestinal puede tener unos efectos significativos y variados en su hue
´sped. Hasta la fecha, los
animales de laboratorio, en particular los ratones, han sido sujetos a sistemas de estudio para la investigacio
´n de la microbiota. Cada vez esta
´ ma
´s claro que los animales de laboratorio a menudo muestran deficientemente aspectos de la biologı´a de los animales salvajes y esta preocupacio
´n se extiende al estudio de la
microbiota intestinal. Aquı´, se revisan los relativamente escasos estudios de la microbiota de los roedores
salvajes, incluida una evaluacio
´n crı´tica de co
´mo la microbiota intestinal difiere entre los roedores de laboratorio y los salvajes. Finalmente, se consideran todas las posibles ventajas y oportunidades de los sistemas
de los animales salvajes para la investigacio
´n de la microbiota intestinal.



Laboratory Animals - June Issue

Table of Contents for the Digital Edition of Laboratory Animals - June Issue

Contents
Laboratory Animals - June Issue - Cover1
Laboratory Animals - June Issue - Cover2
Laboratory Animals - June Issue - Contents
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